Se ha enviado un vínculo para establecer tu contraseña a: Para acceder a tus compras en el futuro, necesitarás una contraseña.

Juan Gärtner

DNA transcription by RNA polymerase (light blue) and pre-mRNA splicing by the spliceosome (darker blue).
Organoid tissue. An organoid is a miniaturized and simplified version of an organ produced in vitro.
Pre-mRNA-spliceosome complex. The spliceosome (dark blue) removes non-coding regions (introns) from pre-mRNA (light violet), leaving the coding regions (exons) to form mature mRNA.
Exosomes, cross section showing proteins and mRNA
The toll-like receptor 7 (TLR7) with an agonist (imiquimod) bound embedded in the membrane of an endosome.
PTEN-induced kinase 1 (PINK1) bound to a protein of the outer mitochondrial membrane
The toll-like receptor 7 (TLR7) with an agonist (imiquimod) bound
Neurons with Lewy bodies
DNA transcription by RNA polymerase, pre-mRNA splicing by a spliceosome and mRNA translation in a ribosome
The peptide tirzepatide (Mounjaro) activating the GLP-1 receptor
Human cells segregating exosomes. Exosomes are extracellular vesicles, that are involved in physiological processes like coagulation, waste management and intercellular communication.
Neurons with Lewy bodies
Oxycodone (Oxycontin) about to bind to an opioid receptor
mRNA entering the cytosol through a nuclear pore
The RNA polymerase II transcribing DNA into RNA.
The ribozyme human ribonuclease P. It cleaves the 5' leader from precursor tRNAs.
The ribozyme human ribonuclease P, two views. Ribonuclease P cleaves the 5' leader from precursor tRNAs.
The tetrameric enzyme beta-galactosidase
Haddock model of the enzyme New Delhi Metallo-beta-Lactamase-1 (NDM-1, blue) in complex with a flavonol inhibitor .
00:11
Hesperidin molecules (surface and stick style). Hesperidin is a potent anti-inflammatory and antioxidant compound.
Neutralizing monoclonal antibody in complex with Herpex Simplex virus 1 (HSV 1) glycoprotein B trimer
Potent novel antibiotics against resistant bacteria: aztreonam and avibactam
El Niño
Epigenetics: DNA methyl transferase I (DMNT1) methylates DNA
DNA transcription by RNA polymerase, pre-mRNA splicing by the spliceosome and mRNA translation by a ribosome.
DNA sequencing nanopore. DNA polymerase (light blue), double-stranded DNA (red), single-stranded DNA (light violet), nanopore CsgG (dark blue).
The schizophrenia associated protein DISC1
Hantavirus envelope glycoprotein Gc in the pre-fusion (left) and post-fusion (right) conformation
Hantavirus envelope glycoprotein Gc (orange) in complex with a therapeutic antibody (light blue)
Major histocompatibility complex proteins (MHC) I and II on the surface of a dendritic cell
Immune checkpoint inhibitors: Interaction between PD-1 and PD-L1 blocked by therapeutic antibodies
Cancer immunotherapy: Therapeutic antibodies attacking cancer cells
Epigenetics: DNA methylation by the DNA methyl transferase I (DMNT1)
Chikungunya viruses. The Chikungunya disease has become a global health concern.
Organoid tissue. An organoid is a miniaturized and simplified version of an organ produced in vitro.
Neutralizing monoclonal antibodies in complex with prefusion RSV F protein
The vascular endothelial growth factor (VEGF) promotes blood vessel formation (angiogenesis)
mRNA entering the cytosol through a nuclear pore
The GLP-receptor agonist tirzepatide (Mounjaro) before binding and bound to the receptor
Immune checkpoint: Interaction between PD-1 and PD-L1 inhibits T-cells killing of tumor cells
Stem cells building up organoids in solution
The Prostate-specific antigen (PSA) with a substrate analogon bound at the active site
The Prostate-specific antigen (PSA)
The double helix structure of DNA
26S proteasome. Proteasomes degrade unneeded or damaged proteins.
Microglia cells (red) play an important role in the pathogenesis of Alzheimer's disease. Neurons (light blue), amyloid plaques (orange).
00:13
A new antibiotic (zosurabalpin) traps lipopolysaccharide in the intermembrane transporter of Acinetobacter baylyi
Strukturvielfalt von Membranproteinen. (links nach rechts): Kalium-Kanal, Opioid-Rezeptor, LDL-Rezeptor, Acetylcholin-Rezeptor, Histamin-Rezeptor.
Darm mit Morbus Crohn
Insulin hexamer dissolving into monomers after injection
Dimeric low density lipoprotein (LDL) receptor (light blue) binding LDL particles
Oncogene: DNA mutation leads to mutated KRAS protein
LDL particles. Low-density lipoprotein particles transport lipids like cholesterol, phospholipids and triglycerids
Neutralizing monoclonal antibody in complex with Herpex Simplex virus 1 (HSV 1) glycoprotein B trimer
Activated spliceosome. The spliceosome removes non-coding regions (introns) from pre-mRNA, leaving the coding regions (exons) to form mature mRNA.
the enzyme New Delhi Metallo-beta-Lactamase-1 (NDM-1, blue) in complex with the flavonol inhibitor morin. NDM1 has devoloped to a global threat by confering resistance to all common β-lactam antibio
The enzyme New Delhi Metallo-beta-Lactamase-1 (NDM-1, blue) in complex with the flavonol inhibitor morin. NDM1 has devoloped to a global threat by confering resistance to all common β-lactam antibio
UCC118 Rool RNA (hexameric RNA). Stable RNA-based therapeutics.
Activated spliceosome. The spliceosome removes non-coding regions (introns) from pre-mRNA, leaving the coding regions (exons) to form mature mRNA.
Asian tiger mosquito bite can cause Chikungkunya virus infection
Haddock model of the enzyme New Delhi Metallo-beta-Lactamase-1 (NDM-1, blue) in complex with the flavonol inhibitor morin.
00:13
The tetrameric enzyme beta-galactosidase with it's inhibitor IPTG bound
The respiratory syncytial virus F protein in the prefusion and fusion conformation.
Multimeric RNA assemblies. Left: UCC118 Rool RNA (hexameric RNA), right: Env38-Golld RNA Multimerization of RNA ensures high stability, high efficacy, and prolonged action of RNA-based drugs.
Wachsende Polypen im Darm.
00:09
A new antibiotic (zosurabalpin) traps lipopolysaccharide in the intermembrane transporter of Acinetobacter baylyi
Alzheimer disease: Tau proteins aggregate to tau filaments
The 26S proteasome going through several conformations after being activated. The ribbon structure of the protein chain is shown in between.
00:14
Dust mites on a dust mote. Dust mites feed on moulds and organic detritus. Their feces (flying particles) induce allergenic reactions. The glossy brown spheres are their eggs.
00:17
Immune checkpoint inhibitors: PD-1, CTLA-4 and PD-1 blocked by therapeutic antibodies
Gesunder Darm. 3d rendering.
Polyp verwandelt sich in Darmkrebs.Adenomatöse Polypen können bösartig werden. Dieses Potenzial nimmt normalerweise mit zunehmender Größe des Polypen zu.
00:19
The vascular endothelial growth factor receptor activated by VEGF. The activation leads to blood vessel formation.
Bandwurm in menschlichen Darm.
Neutralizing monoclonal antibody binding to influenza virus hemagglutinin
Negative regulation of the p53 tumor suppressor. through MDM2 by tagging it with ubiquitin and degradation by a proteasome
Ubiquitination triggers mitophagy of damaged mitochondria. PTEN-induced kinase 1 (PINK1) phosphorylates ubiquitin on the outer mitochondrial membrane.
The prefusion respiratory syncytial virus (RSV) fusion (F) protein
Hesperidin molecules (surface and stick style). Hesperidin is a potent anti-inflammatory and antioxidant compound.
UCC118 Rool RNA (Hexameric RNA). Multimerization of RNA ensures high stability, high efficacy, and prolonged action of RNA-based drugs.
Survivin dimer, tumor marker and potential target in cancer therapy.
Survivin dimer, tumor marker and potential target in cancer therapy.
Multimeric RNA. Stable RNA-based therapeutics.Multimerization of RNA ensures high stability, high efficacy, and prolonged action of RNA-based drugs.
Multimeric RNA. Stable RNA-based therapeutics. Multimerization of RNA ensures high stability, high efficacy, and prolonged action of RNA-based drugs.
Extrachromosomal circular DNA (eccDNA), about 7.500 base pair long. EccDNA is found in many cancers.
PTEN-induced kinase 1 (PINK1) phosphorylates ubiquitin (yellow) on the outer mitochondrial membrane. Parkin (red) will bind afterwards to ubiquitin.
PTEN-induced kinase 1 (PINK1) bound to a protein of the outer mitochondrial membrane. PINK1 is related to Parkinson's disease.
Nicotinic acetylcholine receptor, binding sites of acetylcholine (red) and the agonist nicotine (yellow)
Acetylcholine molecules, surface and ball and stick depiction
Nicotine molecules, surface and ball and stick depiction
The agonist nicotine bound to the nicotinic acetylcholine receptor
Acetylcholine (red) bound to the nicotinic acetylcholine receptor (nAChR)
Virus in liquid medium. Virus with an outer protein-lipid envelope and an inner protein capsid containing RNA/DNA
00:12
The pore forming toxin alpha-hemolysin from Staphylococcus aureus (side view)
Chikungunya virus. It causes the Chikungunya disease. A mosquito mediated infection
Growing tumor, angiogenic switch and neovascularization
Argonaute protein complexed with double stranded microRNA. Guide miRNA strand in red.
Pre-microRNA stick filling style, solution structure. MicroRNA is an essential post-transcriptional regulator of gene expression and also an oncogene.
00:16
Pre-microRNA space filling style, solution structure. MicroRNA is an essential post-transcriptional regulator of gene expression and also an oncogene.
00:16
Pre-microRNA space filling and stick style, solution structure. MicroRNA is an essential post-transcriptional regulator of gene expression and also an oncogene.
00:16